Avatar 2 opens to $441.7 million globally in the first weekend.
North American market sees $134.1 million in the opening weekend.
Over 50% drop on the first Monday at the domestic box office.
Monday's collection was estimated at $16 million.
Black Panther: Wakanda Forever has a lower Monday collection at $11.1 million.
Tom Cruise's Top Gun Maverick has the highest-grossing Monday of 2022 at $33.8 million.
Avatar 2's total domestic box office collection is estimated at $150.1 million.
Avatar 2 soundtracks are to be released on December 20.
Third biggest global start in the post-pandemic era for Avatar 2.